TY  -  JOUR
AU  -  Spargias, Konstantinos S.
AU  -  Maounis, Themos
AU  -  Manginas, Athanassios
AU  -  Athanassopoulos, George
AU  -  Karatasakis, George
AU  -  Koutsogiannis, Nikos
AU  -  Chatzigeorgiou, George
AU  -  Iakovis, Panagiotis
AU  -  Papadakis, Manolis
AU  -  Anifantakis, Alexandros
AU  -  Cokkinos, Dennis V.
T1  -  Preliminary clinical experience with the repetitive administration of levosimendan in patients with end-stage heart failure
PY  -  2003
Y1  -  2003-05-01
JO  -  Archivi - Giornale Italiano di Cardiologia
JA  -  Ital Heart J Suppl
VL  -  4
IS  -  5
SP  -  45
EP  -  49
PB  -  Il Pensiero Scientifico Editore
SN  -  1972-6481
Y2  -  2026/04/16
N2  -  We present our preliminary clinical experience with the initial and repetitive administration of the novel inotropic agent levosimendan in a cohort of 20 patients with end-stage heart failure who were acutely decompensated or whose symptoms were refractory to the usual pharmacological treatments thus necessitating hospitalization. Repetitive levosimendan infusions were administered to 9 patients (minimum 2, maximum 8 pulses). The effects of this therapy on the symptomatic status, vital signs, hemodynamic performance and clinical outcomes are discussed.
ER  -