TY  -  JOUR
AU  -  De Luca, Leonardo
AU  -  Proietti, Paola
AU  -  Palombaro, Gian Luca
AU  -  Battagliese, Alessandro
AU  -  Celotto, Annalisa
AU  -  Bucciarelli-Ducci, Chiara
AU  -  Fedele, Francesco
T1  -  New positive inotropic agents in the treatment of left ventricular dysfunction
PY  -  2004
Y1  -  2004-10-01
JO  -  Archivi - Giornale Italiano di Cardiologia
JA  -  Ital Heart J Suppl
VL  -  5
IS  -  10
SP  -  63
EP  -  67
PB  -  Il Pensiero Scientifico Editore
SN  -  1972-6481
Y2  -  2026/04/13
N2  -  Three major classes of inotropic agents have been clinically evaluated in patients with left ventricular dysfunction: a) agents that increase the intracellular concentration of cyclic adenosine monophosphate by stimulating the beta-adrenergic receptor or inhibiting phosphodiesterase; b) drugs that increase the intracellular sodium concentration; c) the new calcium-sensitizing drugs.<BR>This review will focus on the newest drug for each of the above-mentioned classes of inotropic agents. Moreover, we present a new protocol which provides the use of levosimendan in patients with post-ischemic left ventricular dysfunction.
ER  -